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DecodeMyBio

Pharmacogenomic reports from your 23andMe or AncestryDNA

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DecodeMyBio turns a raw DNA file you already have into pharmacogenomic reports based on CPIC clinical guidelines. It analyzes 19 pharmacogenes and over 150 drug and gene interactions to show how you respond to specific medications, with no new test required. Reports cover medication safety, psychiatric medications, pain and anesthesia, nutrition and methylation, cannabis and CBD, and celiac screening, and include a clinician summary for sharing with a prescriber. Free trait insights are available with an account; full reports are one-time purchases. Uploaded data is encrypted and deleted after 30 days.

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Features

  • Drug and gene interactions - 150+ analyzed, based on CPIC clinical guidelines
  • Pharmacogenes analyzed - 19
  • Source data - Your existing 23andMe or AncestryDNA raw file, no new test
  • Evidence grade - CPIC Level A and B
  • Report types - Medication Safety, Psychiatric, Pain and Anesthesia, Nutrition and Methylation, Cannabis and CBD, Celiac screening
  • Clinician summary - Pocket summary to share with a prescriber
  • Free tier - Basic trait insights: caffeine, lactose, alcohol flush
  • Pricing - One-time reports from $19 to $59, no subscription
  • Data privacy - Encrypted, auto-deleted after 30 days

Use Cases

  • Before starting a new prescription - Check how you metabolize a drug before your doctor's appointment, so you can ask informed questions about dosing
  • Discussing options with your prescriber - Bring the clinician summary to share gene-drug findings your provider can act on
  • Medication isn't working or causing side effects - See if a poor/rapid metabolizer status explains why a drug failed or caused reactions
  • Mental health medication decisions - Review psychiatric drug compatibility (antidepressants, antipsychotics) before trial-and error prescribing
  • Planning surgery or procedures - Understand pain and anesthesia drug responses ahead of an operation
  • Managing chronic pain - Learn how you process common painkillers and opioids to guide safer pain management
  • Optimizing nutrition and supplements - Use methylation and nutrigenomics insights to inform folate, B12, and diet choices
  • Exploring cannabis or CBD - Check how your genes affect THC/CBD metabolism before use
  • Investigating unexplained gut issues - Screen for celiac-related genetic risk markers
  • Getting more from a DNA test you already took - Turn an existing 23andMe or AncestryDNA file into actionable health insights with no new test or blood draw
  • Curious about everyday traits - Use the free tier to check caffeine sensitivity, lactose tolerance, and alcohol flush

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